Lootcase revolves around a bag full of illicit cash that providence lands in the lap of the unsuspecting Nanadan Kumar (Kunal Kemmu) while also setting a motley group of nefarious elements upon him, including rivals ganglords Bala Rathore (Vijay Raaz) and Omar (Sumit Nijhawan), an unscrupulous encounter-specialist cop, Inspector Kolte (Ranvir Shorey) and the malevolent politician, MLA Patil (Gajraj Rao), behind them all. It doesn't help either that Nandan's wife, Lata (Rasika Dugal), is too sanctimonious too be swayed by the lure of extra zeroes.